Wells uses painting, drawing, printmaking, and animation to communicate ideas of environment, relationships, and body/gender. In Willow Wells' creations, the metamorphic journey becomes a visual language, inviting viewers to engage with and reflect upon the nuanced complexities of the human experience.

She earned a Bachelor of Fine Arts from Lyme Academy College of Fine Arts where she studied the figure as well as traditional techniques. She then received her Master of Fine Arts from the University of South Florida. She began employing concepts of metamorphosis into her work, resulting in figures seamlessly merging with botanical elements.

Her work has been exhibited at the Sarasota Art Museum, Bradbury Art Museum, and the Contemporary Art Museum in Tampa, Florida. Her work is also held in the permanent collection of Arkansas State University.